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Functional maintenance can consolidate arterial thrombolysis in cerebral infarction


Department of Neurology, Fourth Hospital of Harbin Medical University, recently, patients with cerebral infarction after arterial thrombolysis in neurological maintenance treatment, and achieved good results.

According to the director of the Department of Yang Zichao introduced, often see a lot of patients with thrombolysis soon after the occurrence of embolism again, the disease repeated. This is mainly due to the commonly used thrombolytic drugs recombinant human tissue plasminogen activator (rt-PA) and urokinase (UK) half-life were 5 to 10 minutes and 14 minutes, thrombolysis can occur again thrombosis form. And neurological function maintenance therapy is an effective way to consolidate the efficacy of thrombolytic therapy. The guidelines for stroke diagnosis and treatment stipulate that anticoagulation and antiplatelet aggregation agents are prohibited within 24 hours after thrombolysis of cerebral infarction. But this usually refers to intravenous thrombolysis. And neurological function maintenance is carried out after arterial thrombolysis, and arterial thrombolysis used rt-PA is generally 20 mg (or urokinase 50 mg, is now generally not used), less than half of intravenous thrombolysis, plus Fiber, anticoagulant does not exceed the guidelines. In clinical, Yang Zichao after more than 400 patients with rt-PA or UK thrombolysis after defibrillation treatment, found that bleeding rate is not higher than the simple rt-PA thrombolytic therapy in patients. Practice has proved that arterial thrombolysis after neurological function maintenance method is completely feasible, and can better maintain the effect of thrombolysis.

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